Pharmacokinetics in Drug Development: Clinical Study Design and Analysis (Volume 1)

Edited by Peter Bonate, Ilex Oncology
Danny Howard, Aventis Pharmaceuticals, Inc.

Clinical Study Design and Analysis (Volume 1)

Volume 1 discusses the role pharmacokinetics plays in selected clinical study designs. Included are first-time-in-man studies, biopharmaceutical, and special population studies. The chapters are written to provide the reader with a familiarity for scientific and operational considerations, and to provide insight into the authors' practical experiences conducting these studies. Volume 1 also discusses the application of pharmacokinetic analysis techniques to drug development - from noncompartmental analysis and interspecies scaling to deconvolution and clinical trial simulation. Volume 1 closes with a discussion on the analysis of clinical safety data in pharmacokinetic studies.

List Price: $175.00, AAPS Member $131.25

Table of Contents